Throughout the years, the EPR has been revised to reflect new research and novel treatment options EPR-3 (2007) is the latest update. The first Expert Panel Report (EPR) Guidelines for asthma were established in 1991, focusing on patient education, environmental control to avoid asthma triggers, and assessment of asthma severity using lung function measures. Asthma attacks were recorded in 51 % of diagnosed patients, resulting in an attack rate as high 43. In terms of lifetime prevalence, asthma was reported in almost 40 million people in the US in 2011 (1 people). people) in the US suffered from asthma in 2011, with children representing 27 % of them. The American Lung Association has reported that nearly 26 million people (84.
Patients with moderate-severe asthma are significantly more likely to have an elevated peripheral eosinophil count than patients with mild asthma. Logistic regression showed that moderate-to-severe asthma was associated with 38 % increased odds of elevated eosinophil level (OR 1.38, 95 % CI: 1.02 to 1.86, p = 0.04). Twenty four percent of patients with moderate-to-severe asthma and 19 % of patients with mild asthma had an elevated peripheral eosinophil count ( p = 0.053). ResultsĪmong 1,144 patients with an asthma diagnosis, 60 % were classified as having moderate-to-severe asthma. Logistic regression models were used to determine if patients with moderate-to-severe asthma had increased likelihood of an elevated peripheral eosinophil count, after accounting for demographics and comorbidities. We classified patients as those with mild asthma and moderate-to-severe asthma based on the pattern of medication use, as recommended by the 2007 National Institutes of Health Expert Panel Report. Patients were required to have at least 1 peripheral eosinophil test (elevated defined as ≥ 400 cells/μL) in the 12 month ‘assessment’ period following the index date. The date of first asthma diagnosis was defined as the ‘index date’. Patients with asthma diagnosis between 20 were extracted from the EMRClaims+ database (eMAX Health, White Plains, NY) containing electronic medical records linked to insurance claims for over 675,000 patients.
The aim of this study was to evaluate the association between blood eosinophil levels and asthma severity defined using Expert Panel Report 3 guidelines. Along with other clinical manifestations of the disease, elevated sputum and blood eosinophil levels are observed in patients experiencing asthma exacerbations.
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To speak with a medical information professional about your medical question or to report an adverse event, side effect, or concern about the quality of a Teva product, call 888-TEVA-USA (88).Asthma represents a significant clinical and economic burden to the US healthcare system. If your question is regarding a specific medical condition or the effects of our products, then you should consult with a healthcare professional, as this form is not designed to answer such questions. In the US, Teva Respiratory currently ranks second among branded respiratory companies based on number of prescriptions dispensed. The portfolio is centered on optimizing respiratory therapies for patients through novel delivery systems and therapies that address unmet needs. In addition, Teva Respiratory is expanding into other respiratory therapy areas where unmet need exists. Teva Respiratory has high-quality, cost-effective treatment options uniquely designed for people with a wide range of respiratory conditions and allergy symptoms.
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